Self-reactive VH4-34–expressing IgG B cells recognize commensal bacteria

The germline immunoglobulin (Ig) variable heavy chain 4–34 (VH4-34) gene segment encodes in humans intrinsically self-reactive antibodies that recognize I/i carbohydrates expressed by erythrocytes with a specific motif in their framework region 1 (FWR1). VH4-34–expressing clones are common in the na...

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Detalles Bibliográficos
Autores principales: Schickel, Jean-Nicolas, Glauzy, Salomé, Ng, Yen-Shing, Chamberlain, Nicolas, Massad, Christopher, Isnardi, Isabelle, Katz, Nathan, Uzel, Gulbu, Holland, Steven M., Picard, Capucine, Puel, Anne, Casanova, Jean-Laurent, Meffre, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502416/
https://www.ncbi.nlm.nih.gov/pubmed/28500047
http://dx.doi.org/10.1084/jem.20160201

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