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Essential role of CCL21 in establishment of central self-tolerance in T cells

The chemokine receptor CCR7 directs T cell relocation into and within lymphoid organs, including the migration of developing thymocytes into the thymic medulla. However, how three functional CCR7 ligands in mouse, CCL19, CCL21Ser, and CCL21Leu, divide their roles in immune organs is unclear. By prod...

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Detalles Bibliográficos
Autores principales: Kozai, Mina, Kubo, Yuki, Katakai, Tomoya, Kondo, Hiroyuki, Kiyonari, Hiroshi, Schaeuble, Karin, Luther, Sanjiv A., Ishimaru, Naozumi, Ohigashi, Izumi, Takahama, Yousuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502431/
https://www.ncbi.nlm.nih.gov/pubmed/28611158
http://dx.doi.org/10.1084/jem.20161864