Cargando…

Sialylation Is Dispensable for Early Murine Embryonic Development in Vitro

The negatively charged nonulose sialic acid (Sia) is essential for murine development in vivo. In order to elucidate the impact of sialylation on differentiation processes in the absence of maternal influences, we generated mouse embryonic stem cell (mESC) lines that lack CMP‐Sia synthetase (CMAS) a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abeln, Markus, Borst, Kristina M., Cajic, Samanta, Thiesler, Hauke, Kats, Elina, Albers, Iris, Kuhn, Maike, Kaever, Volkhard, Rapp, Erdmann, Münster‐Kühnel, Anja, Weinhold, Birgit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2017
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502888/ https://www.ncbi.nlm.nih.gov/pubmed/28374933 http://dx.doi.org/10.1002/cbic.201700083

Ejemplares similares

The monosialoganglioside GM1a protects against complement attack
por: Wedekind, Henri, et al.
Publicado: (2023)

FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression
por: Puan, Kia Joo, et al.
Publicado: (2021)

Reliable N-Glycan Analysis–Removal of Frequently Occurring Oligosaccharide Impurities by Enzymatic Degradation
por: Burock, Robert, et al.
Publicado: (2023)

Enzymatic Cascades for Tailored (13)C(6) and (15)N Enriched Human Milk Oligosaccharides
por: Fischöder, Thomas, et al.
Publicado: (2019)

Fishing for elusive cCMP-degrading phosphodiesterases
por: Schneider, Erich, et al.
Publicado: (2013)

Establishment, Validation, and Initial Application of a Sensitive LC-MS/MS Assay for Quantification of the Naturally Occurring Isomers Itaconate, Mesaconate, and Citraconate
por: Winterhoff, Moritz, et al.
Publicado: (2021)

GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis
por: Abbey, Megha, et al.
Publicado: (2016)

Identification of Cerebrospinal Fluid Metabolites as Biomarkers for Enterovirus Meningitis
por: Ratuszny, Dominica, et al.
Publicado: (2019)

Enforced sialyl‐Lewis‐X (sLeX) display in E‐selectin ligands by exofucosylation is dispensable for CD19‐CAR T‐cell activity and bone marrow homing
por: Sánchez‐Martínez, Diego, et al.
Publicado: (2021)

Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycans
por: Chuzel, Léa, et al.
Publicado: (2021)

News and Views on Polysialic Acid: From Tumor Progression and Brain Development to Psychiatric Disorders, Neurodegeneration, Myelin Repair and Immunomodulation
por: Thiesler, Hauke, et al.
Publicado: (2022)

Mass-spectrometric profiling of cerebrospinal fluid reveals metabolite biomarkers for CNS involvement in varicella zoster virus reactivation
por: Kuhn, Maike, et al.
Publicado: (2018)

Quantitation of cyclic dinucleotides by reversed-phase LC-MS/MS
por: Spangler, Christian, et al.
Publicado: (2009)

Glycomic Characterization of Induced Pluripotent Stem Cells Derived from a Patient Suffering from Phosphomannomutase 2 Congenital Disorder of Glycosylation (PMM2-CDG)
por: Thiesler, Christina T., et al.
Publicado: (2016)

Sialic acids on B cells are crucial for their survival and provide protection against apoptosis
por: Linder, Alexandra T., et al.
Publicado: (2022)

Selectin Ligands Sialyl-Lewis a and Sialyl-Lewis x in Gastrointestinal Cancers
por: Trinchera, Marco, et al.
Publicado: (2017)

Polysialic acid and Siglec-E orchestrate negative feedback regulation of microglia activation
por: Thiesler, Hauke, et al.
Publicado: (2020)

Neuroimmunomodulatory properties of polysialic acid
por: Gretenkort, Lina, et al.
Publicado: (2023)

Expression of the Carbohydrate Lewis Antigen, Sialyl Lewis A, Sialyl Lewis X, Lewis X, and Lewis Y in the Placental Villi of Patients With Unexplained Miscarriages
por: Ma, Zhi, et al.
Publicado: (2021)

Cyclic nucleotides in archaea: Cyclic di‐AMP in the archaeon Haloferax volcanii and its putative role
por: Braun, Frank, et al.
Publicado: (2019)

Identification and quantitation of 2´,3´-cGMP in murine tissues
por: Burhenne, Heike, et al.
Publicado: (2013)

Zebrafish as model organism for cNMP research
por: Dittmar, Fanni, et al.
Publicado: (2015)

Automated synthesis of sialylated oligosaccharides
por: Esposito, Davide, et al.
Publicado: (2012)

The Role of Sialyl-Tn in Cancer
por: Munkley, Jennifer
Publicado: (2016)

Serum sialylation changes in cancer
por: Zhang, Zejian, et al.
Publicado: (2018)

Stable Protein Sialylation in Physcomitrella
por: Bohlender, Lennard L., et al.
Publicado: (2020)

Exclusive Decoration of Simian Immunodeficiency Virus Env with High-Mannose Type N-Glycans Is Not Compatible with Mucosal Transmission in Rhesus Macaques
por: Karsten, Christina B., et al.
Publicado: (2015)

Nucleotidyl cyclase activity of recombinant soluble guanylyl cyclase
por: Rauch, Kerstin, et al.
Publicado: (2009)

Towards In Vivo Imaging of Cancer Sialylation
por: Martinez-Duncker, Ivan, et al.
Publicado: (2011)

Analytical and Functional Aspects of Antibody Sialylation
por: Stadlmann, Johannes, et al.
Publicado: (2010)

Multifaceted Role of Sialylation in Prion Diseases
por: Baskakov, Ilia V., et al.
Publicado: (2016)

Reconstruction of the sialylation pathway in the ancestor of eukaryotes
por: Petit, Daniel, et al.
Publicado: (2018)

Targeting Aberrant Sialylation to Treat Cancer
por: Munkley, Jennifer, et al.
Publicado: (2019)

Sialylation as an Important Regulator of Antibody Function
por: Vattepu, Ravi, et al.
Publicado: (2022)

Aberrant Sialylation in Cancer: Therapeutic Opportunities
por: Munkley, Jennifer
Publicado: (2022)

Alterations of the Sialylation Machinery in Brugada Syndrome
por: Ghiroldi, Andrea, et al.
Publicado: (2022)

Response of high-risk of recurrence/progression bladder tumours expressing sialyl-Tn and sialyl-6-T to BCG immunotherapy
por: Lima, L, et al.
Publicado: (2013)

Phosphatidylcholine PC ae C44:6 in cerebrospinal fluid is a sensitive biomarker for bacterial meningitis
por: de Araujo, Leonardo Silva, et al.
Publicado: (2020)

Evidence for two catalytic centers and Mn(2+) as physiological cofactor of soluble guanylyl cyclase
por: Beste, Kerstin Yvonne, et al.
Publicado: (2011)

New Insights into the Cyclic Di-adenosine Monophosphate (c-di-AMP) Degradation Pathway and the Requirement of the Cyclic Dinucleotide for Acid Stress Resistance in Staphylococcus aureus
por: Bowman, Lisa, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_0v3q9ra0lech9ka2jatpv51q89