Structure of a pre-catalytic spliceosome

Intron removal requires assembly of the spliceosome on pre-mRNA and extensive remodelling to form the spliceosome’s catalytic centre. Here we report the cryo-electron microscopy structure of the yeast pre-catalytic B complex spliceosome at near-atomic resolution. The mobile U2 snRNP associates with...

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Detalles Bibliográficos
Autores principales: Plaschka, Clemens, Lin, Pei-Chun, Nagai, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503131/
https://www.ncbi.nlm.nih.gov/pubmed/28530653
http://dx.doi.org/10.1038/nature22799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503131/
https://www.ncbi.nlm.nih.gov/pubmed/28530653
http://dx.doi.org/10.1038/nature22799

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