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Asiatic acid protects against cognitive deficits and reductions in cell proliferation and survival in the rat hippocampus caused by 5-fluorouracil chemotherapy
The chemotherapy drug, 5-fluorouracil (5-FU), has been reported to cause cognitive impairments in cancer patients. The drug also reduces cell proliferation and survival in the brain. Asiatic acid (AA) is a triterpene compound found in Centella asiatica that can protect against reduction of neurogene...
Autores principales: | Chaisawang, Pornthip, Sirichoat, Apiwat, Chaijaroonkhanarak, Wunnee, Pannangrong, Wanassanun, Sripanidkulchai, Bungorn, Wigmore, Peter, Welbat, Jariya Umka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503269/ https://www.ncbi.nlm.nih.gov/pubmed/28700628 http://dx.doi.org/10.1371/journal.pone.0180650 |
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