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Synthesis and antimicrobial activity of chiral quaternary N-spiro ammonium bromides with 3′,4′-dihydro-1′H-spiro[isoindoline-2,2′-isoquinoline] skeleton

A new class of highly functionalized tetrahydroisoquinolines with a quaternary carbon stereocenter was synthesized starting from an easily accessible L-tartaric acid. Nine strains of bacteria (Staphylococcus aureus, Streptococcus pyogenes, Streptococcus mutans, Streptococcus salivarius, Bacillus sub...

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Detalles Bibliográficos
Autores principales:	Bielawski, Krzysztof, Leszczyńska, Katarzyna, Kałuża, Zbigniew, Bielawska, Anna, Michalak, Olga, Daniluk, Tamara, Staszewska-Krajewska, Olga, Czajkowska, Anna, Pawłowska, Natalia, Gornowicz, Agnieszka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503491/ https://www.ncbi.nlm.nih.gov/pubmed/28740363 http://dx.doi.org/10.2147/DDDT.S133250

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