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Clinical and economic burden of dyspnea and other COPD symptoms in a managed care setting

PURPOSE: The degree to which symptoms such as dyspnea affect patients with COPD is individualized. To address the gap between clinical symptom measures and self-perceived disease burden, we investigated the symptom status of adult patients with COPD and followed with an administrative claims analysi...

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Autores principales: Stephenson, Judith J, Wertz, Debra, Gu, Tao, Patel, Jeetvan, Dalal, Anand A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503502/
https://www.ncbi.nlm.nih.gov/pubmed/28740375
http://dx.doi.org/10.2147/COPD.S134618
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author Stephenson, Judith J
Wertz, Debra
Gu, Tao
Patel, Jeetvan
Dalal, Anand A
author_facet Stephenson, Judith J
Wertz, Debra
Gu, Tao
Patel, Jeetvan
Dalal, Anand A
author_sort Stephenson, Judith J
collection PubMed
description PURPOSE: The degree to which symptoms such as dyspnea affect patients with COPD is individualized. To address the gap between clinical symptom measures and self-perceived disease burden, we investigated the symptom status of adult patients with COPD and followed with an administrative claims analysis of health care resource utilization and costs. METHODS: This was a hybrid US observational study consisting of a cross-sectional patient survey followed by a retrospective analysis of administrative claims data. The primary COPD symptom measures were the modified Medical Research Council (mMRC) Dyspnea scale and the COPD Assessment Test (CAT). RESULTS: A total of 673 patients completed the survey. Of these, 65% reported mMRC grades 0–1 (low symptomatology) and 35% reported mMRC grades 2–4 (high symptomatology); 25% reported CAT score <10 (low symptomatology) and 75% reported CAT score ≥10 (high symptomatology). More patients with high symptomatology (by either measure) had at least one COPD-related inpatient hospitalization, emergency room visit, physician office visit, or other outpatient services, and filled at least one COPD-related prescription medication vs patients with low symptomatology. COPD-related costs were higher for patients with high symptomatology than patients with low symptomatology. In a multivariate analysis, COPD-related costs were also higher in patients reporting severe symptoms. CONCLUSION: Patients with high COPD symptomatology utilized more health care resources and had higher COPD-related health care costs during the 6-month post-survey period than patients with low symptomatology.
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spelling pubmed-55035022017-07-24 Clinical and economic burden of dyspnea and other COPD symptoms in a managed care setting Stephenson, Judith J Wertz, Debra Gu, Tao Patel, Jeetvan Dalal, Anand A Int J Chron Obstruct Pulmon Dis Original Research PURPOSE: The degree to which symptoms such as dyspnea affect patients with COPD is individualized. To address the gap between clinical symptom measures and self-perceived disease burden, we investigated the symptom status of adult patients with COPD and followed with an administrative claims analysis of health care resource utilization and costs. METHODS: This was a hybrid US observational study consisting of a cross-sectional patient survey followed by a retrospective analysis of administrative claims data. The primary COPD symptom measures were the modified Medical Research Council (mMRC) Dyspnea scale and the COPD Assessment Test (CAT). RESULTS: A total of 673 patients completed the survey. Of these, 65% reported mMRC grades 0–1 (low symptomatology) and 35% reported mMRC grades 2–4 (high symptomatology); 25% reported CAT score <10 (low symptomatology) and 75% reported CAT score ≥10 (high symptomatology). More patients with high symptomatology (by either measure) had at least one COPD-related inpatient hospitalization, emergency room visit, physician office visit, or other outpatient services, and filled at least one COPD-related prescription medication vs patients with low symptomatology. COPD-related costs were higher for patients with high symptomatology than patients with low symptomatology. In a multivariate analysis, COPD-related costs were also higher in patients reporting severe symptoms. CONCLUSION: Patients with high COPD symptomatology utilized more health care resources and had higher COPD-related health care costs during the 6-month post-survey period than patients with low symptomatology. Dove Medical Press 2017-07-04 /pmc/articles/PMC5503502/ /pubmed/28740375 http://dx.doi.org/10.2147/COPD.S134618 Text en © 2017 Stephenson et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Stephenson, Judith J
Wertz, Debra
Gu, Tao
Patel, Jeetvan
Dalal, Anand A
Clinical and economic burden of dyspnea and other COPD symptoms in a managed care setting
title Clinical and economic burden of dyspnea and other COPD symptoms in a managed care setting
title_full Clinical and economic burden of dyspnea and other COPD symptoms in a managed care setting
title_fullStr Clinical and economic burden of dyspnea and other COPD symptoms in a managed care setting
title_full_unstemmed Clinical and economic burden of dyspnea and other COPD symptoms in a managed care setting
title_short Clinical and economic burden of dyspnea and other COPD symptoms in a managed care setting
title_sort clinical and economic burden of dyspnea and other copd symptoms in a managed care setting
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503502/
https://www.ncbi.nlm.nih.gov/pubmed/28740375
http://dx.doi.org/10.2147/COPD.S134618
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