Mutation of the Sp1 binding site in the 5′ flanking region of SRY causes sex reversal in rabbits

Sex-determining region Y is a crucial gene that initiates male sex determination in mammals. Mutations of the Sp1-binding site in the 5′ flanking region of SRY are associated with clinical male-to-female sex reversal syndrome, although such occurrences are rare and, until now, have not been reported...

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Detalles Bibliográficos
Autores principales: Song, Yuning, Liu, Tingjun, Wang, Yong, Deng, Jichao, Chen, Mao, Yuan, Lin, Lu, Yi, Xu, Yuxin, Yao, Haobin, Li, Zhanjun, Lai, Liangxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper: Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503524/
https://www.ncbi.nlm.nih.gov/pubmed/28445127
http://dx.doi.org/10.18632/oncotarget.16979

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