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Lipid degradation promotes prostate cancer cell survival

Prostate cancer is the most common male cancer and androgen receptor (AR) is the major driver of the disease. Here we show that Enoyl-CoA delta isomerase 2 (ECI2) is a novel AR-target that promotes prostate cancer cell survival. Increased ECI2 expression predicts mortality in prostate cancer patient...

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Detalles Bibliográficos
Autores principales:	Itkonen, Harri M, Brown, Michael, Urbanucci, Alfonso, Tredwell, Gregory, Lau, Chung Ho, Barfeld, Stefan, Hart, Claire, Guldvik, Ingrid J., Takhar, Mandeep, Heemers, Hannelore V., Erho, Nicholas, Bloch, Katarzyna, Davicioni, Elai, Derua, Rita, Waelkens, Etienne, Mohler, James L., Clarke, Noel, Swinnen, Johan V., Keun, Hector C., Rekvig, Ole P., Mills, Ian G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503531/ https://www.ncbi.nlm.nih.gov/pubmed/28415728 http://dx.doi.org/10.18632/oncotarget.16123

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