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TAZ induces lung cancer stem cell properties and tumorigenesis by up-regulating ALDH1A1

Recent studies suggest that lung cancer stem cells (CSCs) may play major roles in lung cancer. Therefore, identification of lung CSC drivers may provide promising targets for lung cancer. TAZ is a transcriptional co-activator and key downstream effector of the Hippo pathway, which plays critical rol...

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Detalles Bibliográficos
Autores principales:	Yu, Jihang, Alharbi, Adel, Shan, Hongchao, Hao, Yawei, Snetsinger, Brooke, Rauh, Michael J., Yang, Xiaolong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503543/ https://www.ncbi.nlm.nih.gov/pubmed/28415606 http://dx.doi.org/10.18632/oncotarget.16430

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