Novel recombinant immunotoxin of EGFR specific nanobody fused with cucurmosin, construction and antitumor efficiency in vitro

Epidermal growth factor receptor (EGFR) overexpression is related to the increased aggressiveness, metastases, and poor prognosis in various cancers. In this study, we successfully constructed a new EGFR nanobody-based immunotoxin rE/CUS containing cucurmosin (CUS), The immunotoxin was expressed by...

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Detalles Bibliográficos
Autores principales: Deng, Cuimin, Xiong, Jiani, Gu, Xiaofan, Chen, Xiaoying, Wu, Shuifa, Wang, Zhe, Wang, Duanduan, Tu, Jinjin, Xie, Jieming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503554/
https://www.ncbi.nlm.nih.gov/pubmed/28445134
http://dx.doi.org/10.18632/oncotarget.16930

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