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Selective eradication of cancer cells by delivery of adenovirus-based toxins

BACKGROUND AND OBJECTIVE: KRAS mutation is an early event in colorectal cancer carcinogenesis. We previously reported that a recombinant adenovirus, carrying a pro-apoptotic gene (PUMA) under the regulation of Ets/AP1 (RAS-responsive elements) suppressed the growth of cancer cells harboring hyperact...

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Detalles Bibliográficos
Autores principales:	Shapira, Shiran, Shapira, Assaf, Kazanov, Diana, Hevroni, Gil, Kraus, Sarah, Arber, Nadir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503555/ https://www.ncbi.nlm.nih.gov/pubmed/28445136 http://dx.doi.org/10.18632/oncotarget.16934

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