Cargando…

RNA sequencing-based cell proliferation analysis across 19 cancers identifies a subset of proliferation-informative cancers with a common survival signature

Despite advances in cancer diagnosis and treatment strategies, robust prognostic signatures remain elusive in most cancers. Cell proliferation has long been recognized as a prognostic marker in cancer, but the generation of comprehensive, publicly available datasets allows examination of the links b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ramaker, Ryne C., Lasseigne, Brittany N., Hardigan, Andrew A., Palacio, Laura, Gunther, David S., Myers, Richard M., Cooper, Sara J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503562/ https://www.ncbi.nlm.nih.gov/pubmed/28454104 http://dx.doi.org/10.18632/oncotarget.16961

Ejemplares similares

aRNApipe: a balanced, efficient and distributed pipeline for processing RNA-seq data in high-performance computing environments
por: Alonso, Arnald, et al.
Publicado: (2017)

Pooled CRISPR screening in pancreatic cancer cells implicates co-repressor complexes as a cause of multiple drug resistance via regulation of epithelial-to-mesenchymal transition
por: Ramaker, Ryne C., et al.
Publicado: (2021)

Genome-wide DNA methylation measurements in prostate tissues uncovers novel prostate cancer diagnostic biomarkers and transcription factor binding patterns
por: Kirby, Marie K., et al.
Publicado: (2017)

A genome-wide interactome of DNA-associated proteins in the human liver
por: Ramaker, Ryne C., et al.
Publicado: (2017)

Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation
por: Savic, Daniel, et al.
Publicado: (2016)

Dissecting the regulatory activity and sequence content of loci with exceptional numbers of transcription factor associations
por: Ramaker, Ryne C., et al.
Publicado: (2020)

CRISPR/Cas9-targeted removal of unwanted sequences from small-RNA sequencing libraries
por: Hardigan, Andrew A, et al.
Publicado: (2019)

Cancer cell proliferation is inhibited by specific modulation frequencies
por: Zimmerman, J W, et al.
Publicado: (2012)

Proliferation Cycle Transcriptomic Signatures are Strongly associated With Gastric Cancer Patient Survival
por: Hu, Jianwen, et al.
Publicado: (2021)

Kinase Gene Expression Profiling of Metastatic Clear Cell Renal Cell Carcinoma Tissue Identifies Potential New Therapeutic Targets
por: Ghatalia, Pooja, et al.
Publicado: (2016)

Nucleic acid liquid biopsies in Alzheimer's disease: current state, challenges, and opportunities
por: Soelter, Tabea M., et al.
Publicado: (2022)

Liquid biopsies in epilepsy: biomarkers for etiology, diagnosis, prognosis, and therapeutics
por: Whitlock, Jordan H., et al.
Publicado: (2021)

Augmentation of the RNA m6A reader signature is associated with poor survival by enhancing cell proliferation and EMT across cancer types
por: Oh, Jaeik, et al.
Publicado: (2022)

Migration rather than proliferation transcriptomic signatures are strongly associated with breast cancer patient survival
por: Nair, Nishanth Ulhas, et al.
Publicado: (2019)

Inferring chromosomal instability from copy number aberrations as a measure of chromosomal instability across human cancers
por: Taluri, Sasha, et al.
Publicado: (2023)

Post-mortem molecular profiling of three psychiatric disorders
por: Ramaker, Ryne C., et al.
Publicado: (2017)

YAP Dysregulation by Phosphorylation or ΔNp63-mediated Gene Repression Promotes Proliferation, Survival and Migration in Head and Neck Cancer Subsets
por: Ehsanian, Reza, et al.
Publicado: (2010)

Interleukin 15 Controls both Proliferation and Survival of a Subset of Memory-Phenotype CD8(+) T Cells
por: Judge, Adam D., et al.
Publicado: (2002)

Functional common gamma chain is not required for mast cell proliferation and survival
por: Chapdelaine, H, et al.
Publicado: (2012)

TASK-1 Regulates Apoptosis and Proliferation in a Subset of Non-Small Cell Lung Cancers
por: Leithner, Katharina, et al.
Publicado: (2016)

Pyroptosis-related genes regulate proliferation and invasion of pancreatic cancer and serve as the prognostic signature for modeling patient survival
por: Song, Wenjing, et al.
Publicado: (2022)

Genomic regulation of invasion by STAT3 in triple negative breast cancer
por: McDaniel, Joy M., et al.
Publicado: (2016)

Enhanced nuclear translation is associated with proliferation and progression across multiple cancers
por: Zou, Sailan, et al.
Publicado: (2023)

Neuronatin in a Subset of Glioblastoma Multiforme Tumor Progenitor Cells Is Associated with Increased Cell Proliferation and Shorter Patient Survival
por: Xu, David S., et al.
Publicado: (2012)

Robust prognostic value of a knowledge-based proliferation signature across large patient microarray studies spanning different cancer types
por: Starmans, M H W, et al.
Publicado: (2008)

Inhibition of human lung cancer cell proliferation and survival by wine
por: Barron, Carly C, et al.
Publicado: (2014)

The Role of Mitochondrial Fat Oxidation in Cancer Cell Proliferation and Survival
por: De Oliveira, Matheus Pinto, et al.
Publicado: (2020)

Stromal Genes Add Prognostic Information to Proliferation and Histoclinical Markers: A Basis for the Next Generation of Breast Cancer Gene Signatures
por: Mefford, Dwain, et al.
Publicado: (2012)

Prognostic Value of Gene Signatures and Proliferation in Lymph-Node-Negative Breast Cancer
por: Jonsdottir, Kristin, et al.
Publicado: (2014)

TUFT1 is expressed in breast cancer and involved in cancer cell proliferation and survival
por: Liu, Weiguang, et al.
Publicado: (2017)

CANCER-ASSOCIATED FIBROBLAST EXOSOMES REGULATE SURVIVAL AND PROLIFERATION OF PANCREATIC CANCER CELLS
por: Richards, Katherine E., et al.
Publicado: (2016)

Mouse cytomegalovirus is infectious for rats and alters lymphocyte subsets and spleen cell proliferation
por: Smith, C. B., et al.
Publicado: (1986)

Estimating the contribution of CD4 T cell subset proliferation and differentiation to HIV persistence
por: Reeves, Daniel B., et al.
Publicado: (2023)

The landscape of SETBP1 gene expression and transcription factor activity across human tissues
por: Whitlock, Jordan H., et al.
Publicado: (2023)

Targeting proliferation and survival pathways in head and neck cancer for therapeutic benefit
por: Johnson, Daniel E.
Publicado: (2012)

Roles of TRPM8 Ion Channels in Cancer: Proliferation, Survival, and Invasion
por: Yee, Nelson S.
Publicado: (2015)

Effect of polyunsaturated fatty acids on proliferation and survival of prostate cancer cells
por: Bratton, Brenden A., et al.
Publicado: (2019)

Aberrant Dyskerin Expression Is Related to Proliferation and Poor Survival in Endometrial Cancer
por: Alnafakh, Rafah, et al.
Publicado: (2021)

The Adipokine Component in the Molecular Regulation of Cancer Cell Survival, Proliferation and Metastasis
por: Umar, Muhammad Ihtisham, et al.
Publicado: (2021)

Reduced expression of a gene proliferation signature is associated with enhanced malignancy in colon cancer
por: Anjomshoaa, A, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_4m8kcu9r9g2aua446rof339kgo