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Downregulation of Bmi1 in breast cancer stem cells suppresses tumor growth and proliferation

Targeting cancer stem cells during initial treatment is important to reduce incidence of recurrent disease. Bmi1 has been associated with cancer stem cell self-renewal and aggressive disease. The purpose of this study was to determine the effects of downregulation of Bmi1 in breast cancer stem cells...

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Detalles Bibliográficos
Autores principales: Srinivasan, Mathangi, Bharali, Dhruba J., Sudha, Thangirala, Khedr, Maha, Guest, Ian, Sell, Stewart, Glinsky, Gennadi V., Mousa, Shaker A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503567/
https://www.ncbi.nlm.nih.gov/pubmed/28418883
http://dx.doi.org/10.18632/oncotarget.16317