A novel RON splice variant lacking exon 2 activates the PI3K/AKT pathway via PTEN phosphorylation in colorectal carcinoma cells

Abnormal expression of the Recepteur d'Origine Nantais (RON) receptor tyrosine kinase is accompanied by the generation of multiple splice or truncated variants, which mediate many critical cellular functions that contribute to tumor progression and metastasis. Here, we report a new RON splice v...

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Detalles Bibliográficos
Autores principales: Ling, Yu, Kuang, Yeye, Chen, Lin-Lin, Lao, Wei-Feng, Zhu, Yao-Ru, Wang, Le-Qi, Wang, Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503598/
https://www.ncbi.nlm.nih.gov/pubmed/28388571
http://dx.doi.org/10.18632/oncotarget.16603

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