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Pantoprazole blocks the JAK2/STAT3 pathway to alleviate skeletal muscle wasting in cancer cachexia by inhibiting inflammatory response

OBJECTIVE: Cancer cachexia is often present in patients with advanced malignant tumors, and the subsequent body weight reduction results in poor quality of life. However, there has been no progress in developing effective clinical therapeutic strategies for skeletal muscle wasting in cancer cachexia...

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Detalles Bibliográficos
Autores principales: Guo, Dunwei, Wang, Chaoyi, Wang, Qiang, Qiao, Zhongpeng, Tang, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503639/
https://www.ncbi.nlm.nih.gov/pubmed/28489606
http://dx.doi.org/10.18632/oncotarget.17387