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Pantoprazole blocks the JAK2/STAT3 pathway to alleviate skeletal muscle wasting in cancer cachexia by inhibiting inflammatory response
OBJECTIVE: Cancer cachexia is often present in patients with advanced malignant tumors, and the subsequent body weight reduction results in poor quality of life. However, there has been no progress in developing effective clinical therapeutic strategies for skeletal muscle wasting in cancer cachexia...
Autores principales: | Guo, Dunwei, Wang, Chaoyi, Wang, Qiang, Qiao, Zhongpeng, Tang, Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503639/ https://www.ncbi.nlm.nih.gov/pubmed/28489606 http://dx.doi.org/10.18632/oncotarget.17387 |
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