Cargando…

Weekly ascorbic acid infusion in castration-resistant prostate cancer patients: a single-arm phase II trial

BACKGROUND: Ascorbic acid (AA) has in vivo cytotoxic properties at concentrations that can only be achieved through intravenous (IV) administration in humans. Treatment with intravenous AA is widely and increasingly used in complementary medicine despite a lack of clinical evidence for the efficacy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nielsen, Torben K., Højgaard, Martin, Andersen, Jon T., Jørgensen, Niklas Rye, Zerahn, Bo, Kristensen, Bent, Henriksen, Trine, Lykkesfeldt, Jens, Mikines, Kári J., Poulsen, Henrik E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503969/ https://www.ncbi.nlm.nih.gov/pubmed/28725594 http://dx.doi.org/10.21037/tau.2017.04.42

Ejemplares similares

Simvastatin and oxidative stress in humans: A randomized, double-blinded, placebo-controlled clinical trial
por: Rasmussen, Sanne Tofte, et al.
Publicado: (2016)

An Algorithm for Individual Dosage in Cadmium–Zinc–Telluride SPECT-Gated Radionuclide Angiography
por: Hansen, Maria Normand, et al.
Publicado: (2021)

Randomized Trial of Acute Changes in Plasma Phosphate After Phosphorus-Standardized Meals in Peritoneal Dialysis
por: Lundin, Martin Thorbjørn, et al.
Publicado: (2021)

The Nephroprotective Effect of Mannitol in Head and Neck Cancer Patients Receiving Cisplatin Therapy
por: Hägerström, Erik, et al.
Publicado: (2019)

Ascorbate maintains a low plasma oxygen level
por: Injarabian, Louise, et al.
Publicado: (2020)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration-resistant prostate cancer
por: Gordon, Nicolas, et al.
Publicado: (2023)

The P2X7 Receptor: A Key Player in Immune-Mediated Bone Loss?
por: Kvist, Torben Madsen, et al.
Publicado: (2014)

Specific prediction of mortality by oxidative stress‐induced damage to RNA vs. DNA in humans
por: Jorgensen, Anders, et al.
Publicado: (2023)

l-dehydroascorbic acid can substitute l-ascorbic acid as dietary vitamin C source in guinea pigs
por: Frikke-Schmidt, Henriette, et al.
Publicado: (2015)

Mice Do Not Habituate to Metabolism Cage Housing–A Three Week Study of Male BALB/c Mice
por: Kalliokoski, Otto, et al.
Publicado: (2013)

Metformin-induced changes of the gut microbiota in healthy young men: results of a non-blinded, one-armed intervention study
por: Bryrup, Thomas, et al.
Publicado: (2019)

Changes in quality of life 6 months after parathyroidectomy for primary hyperparathyroidism
por: Christensen, Julie Wulf, et al.
Publicado: (2022)

Guaiphenesin-ketamine-xylazine infusion to maintain anesthesia in mules undergoing field castration
por: Vullo, Cecilia, et al.
Publicado: (2017)

Gestational diabetes is associated with change in the gut microbiota composition in third trimester of pregnancy and postpartum
por: Crusell, Mie Korslund Wiinblad, et al.
Publicado: (2018)

Comparative Studies of the Gut Microbiota in the Offspring of Mothers With and Without Gestational Diabetes
por: Crusell, Mie Korslund Wiinblad, et al.
Publicado: (2020)

2-O-α-D-Glucopyranosyl-l-ascorbic acid as an antitumor agent for infusion therapy
por: Miura, Kaori, et al.
Publicado: (2017)

Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs
por: Pedersen, Kamilla, et al.
Publicado: (2022)

Effects of administration of ascorbic acid and low‐dose hydrocortisone after infusion of sublethal doses of lipopolysaccharide to horses
por: Anderson, Melinda J., et al.
Publicado: (2020)

Membrane Permeabilities of Ascorbic Acid and Ascorbate
por: Hannesschlaeger, Christof, et al.
Publicado: (2018)

Increased Tumoral Microenvironmental pH Improves Cytotoxic Effect of Pharmacologic Ascorbic Acid in Castration-Resistant Prostate Cancer Cells
por: Li, Zhoulei, et al.
Publicado: (2020)

Objectively measured physical activity level and sedentary behavior in Norwegian children during a week in preschool()
por: Andersen, Eivind, et al.
Publicado: (2017)

(11)C-Choline PET/CT vs. (99m)Tc-MIBI/(123)Iodide Subtraction SPECT/CT for Preoperative Detection of Abnormal Parathyroid Glands in Primary Hyperparathyroidism: A Prospective, Single-Centre Clinical Trial in 60 Patients
por: Ismail, Afefah, et al.
Publicado: (2020)

Neuromas at the castration site in geldings
por: Bengtsdotter, Emma Angelina, et al.
Publicado: (2019)

In situ aromatase expression in primary tumor is associated with estrogen receptor expression but is not predictive of response to endocrine therapy in advanced breast cancer
por: Lykkesfeldt, Anne E, et al.
Publicado: (2009)

The Radiographic Changes of Catheter Tip in Different Positions of Arm Infusion Port
por: Gong, Yuan, et al.
Publicado: (2022)

Collagen remodelling and plasma ascorbic acid levels in patients suspected of inherited bleeding disorders harbouring germline variants in collagen‐related genes
por: Fager Ferrari, Marcus, et al.
Publicado: (2020)

Infusion Therapies in the Treatment of Parkinson’s Disease
por: van Laar, Teus, et al.
Publicado: (2023)

Retracted: The Radiographic Changes of Catheter Tip in Different Positions of Arm Infusion Port
por: Imaging, Contrast Media & Molecular
Publicado: (2023)

Vitamin C Administration by Intravenous Infusion Increases Tumor Ascorbate Content in Patients With Colon Cancer: A Clinical Intervention Study
por: Dachs, Gabi U., et al.
Publicado: (2021)

Bevacizumab and Weekly Docetaxel in Patients with Metastatic Castrate-Resistant Prostate Cancer Previously Exposed to Docetaxel
por: Francini, Filippo, et al.
Publicado: (2011)

The effect of normalization of sodium on bone turnover markers in patients with epilepsy. A randomized single-blinded placebo-controlled trial
por: Diemar, Sarah Seberg, et al.
Publicado: (2020)

Associations between inflammatory markers, body composition, and physical function: the Copenhagen Sarcopenia Study
por: Kamper, Rikke S., et al.
Publicado: (2021)

Clinical and biochemical outcomes of cinacalcet treatment of familial hypocalciuric hypercalcemia: a case series
por: Rasmussen, Anne Qvist, et al.
Publicado: (2011)

High On-Treatment Platelet Reactivity in Danish Hyper-Acute Ischaemic Stroke Patients
por: Rath, Charlotte L., et al.
Publicado: (2018)

Identification and Functional Characterization of a Novel Mutation in the Human Calcium-Sensing Receptor That Co-Segregates With Autosomal-Dominant Hypocalcemia
por: Rasmussen, Anne Qvist, et al.
Publicado: (2018)

Clopidogrel responder status is uninfluenced by CYP2C19*2 in Danish patients with stroke
por: Rath, Charlotte Lützhøft, et al.
Publicado: (2020)

Preoperative imaging in primary hyperparathyroidism: Are (11)C‐Choline PET/CT and (99m)Tc‐MIBI/(123)Iodide subtraction SPECT/CT interchangeable or do they supplement each other?
por: Christensen, Julie W., et al.
Publicado: (2022)

Effects of castration on atherosclerosis in Yucatan minipigs with genetic hypercholesterolemia
por: Shim, Jeong T., et al.
Publicado: (2020)

Alteration in ascorbate and ascorbate peroxidase in programmed cell death and oxidative stress
por: Paradiso, Annalisa, et al.
Publicado: (2005)

Systemic DNA and RNA damage from oxidation after serotonergic treatment of unipolar depression
por: Jorgensen, Anders, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_oqoq4eu1ap3kgpb3sv4522hij6