High Frequency Components of Hemodynamic Shear Stress Profiles are a Major Determinant of Shear-Mediated Platelet Activation in Therapeutic Blood Recirculating Devices

We systematically analyzed the relative contributions of frequency component elements of hemodynamic shear stress waveforms encountered in cardiovascular blood recirculating devices as to overall platelet activation over time. We demonstrated that high frequency oscillations are the major determinan...

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Detalles Bibliográficos
Autores principales: Consolo, Filippo, Sheriff, Jawaad, Gorla, Silvia, Magri, Nicolò, Bluestein, Danny, Pappalardo, Federico, Slepian, Marvin J., Fiore, Gianfranco B., Redaelli, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5503983/
https://www.ncbi.nlm.nih.gov/pubmed/28694489
http://dx.doi.org/10.1038/s41598-017-05130-5

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