Key Role for the Organic Anion Transporters, OAT1 and OAT3, in the in vivo Handling of Uremic Toxins and Solutes

In vitro data indicates that the kidney proximal tubule (PT) transporters of uremic toxins and solutes (e.g., indoxyl sulfate, p-cresol sulfate, kynurenine, creatinine, urate) include two “drug” transporters of the organic anion transporter (OAT) family: OAT1 (SLC22A6, originally NKT) and OAT3 (SLC2...

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Detalles Bibliográficos
Autores principales: Wu, Wei, Bush, Kevin T., Nigam, Sanjay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504054/
https://www.ncbi.nlm.nih.gov/pubmed/28694431
http://dx.doi.org/10.1038/s41598-017-04949-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504054/
https://www.ncbi.nlm.nih.gov/pubmed/28694431
http://dx.doi.org/10.1038/s41598-017-04949-2

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