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Recombinant Invasive Lactococcus lactis Carrying a DNA Vaccine Coding the Ag85A Antigen Increases INF-γ, IL-6, and TNF-α Cytokines after Intranasal Immunization
Tuberculosis (TB) remains a major threat throughout the world and in 2015 it caused the death of 1.4 million people. The Bacillus Calmette-Guérin is the only existing vaccine against this ancient disease; however, it does not provide complete protection in adults. New vaccines against TB are eminent...
Autores principales: | Mancha-Agresti, Pamela, de Castro, Camila Prosperi, dos Santos, Janete S. C., Araujo, Maíra A., Pereira, Vanessa B., LeBlanc, Jean G., Leclercq, Sophie Y., Azevedo, Vasco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504179/ https://www.ncbi.nlm.nih.gov/pubmed/28744263 http://dx.doi.org/10.3389/fmicb.2017.01263 |
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