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Coordinated force generation of skeletal myosins in myofilaments through motor coupling

In contrast to processive molecular motors, skeletal myosins form a large motor ensemble for contraction of muscles against high loads. Despite numerous information on the molecular properties of skeletal myosin, its ensemble effects on collective force generation have not been rigorously clarified....

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Detalles Bibliográficos
Autores principales: Kaya, Motoshi, Tani, Yoshiaki, Washio, Takumi, Hisada, Toshiaki, Higuchi, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504292/
https://www.ncbi.nlm.nih.gov/pubmed/28681850
http://dx.doi.org/10.1038/ncomms16036