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YAP determines the cell fate of injured mouse hepatocytes in vivo

The presence of senescent, transformed or damaged cells can impair tissue function or lead to tumorigenesis; therefore, organisms have evolved quality control mechanisms to eliminate them. Here, we show that YAP activation induced by inactivation of the Hippo pathway specifically in damaged hepatocy...

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Detalles Bibliográficos
Autores principales:	Miyamura, Norio, Hata, Shoji, Itoh, Tohru, Tanaka, Minoru, Nishio, Miki, Itoh, Michiko, Ogawa, Yoshihiro, Terai, Shuji, Sakaida, Isao, Suzuki, Akira, Miyajima, Atsushi, Nishina, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504293/ https://www.ncbi.nlm.nih.gov/pubmed/28681838 http://dx.doi.org/10.1038/ncomms16017

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