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Chronic hepatitis B, nonalcoholic steatohepatitis and physical fitness of military males: CHIEF study
AIM: To investigate the association of chronic hepatitis B and nonalcoholic steatohepatitis with physical fitness in a Taiwanese military male cohort. METHODS: We made a cross-sectional examination of this association using 3669 young adult military males according to cardiorespiratory fitness and h...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504374/ https://www.ncbi.nlm.nih.gov/pubmed/28740347 http://dx.doi.org/10.3748/wjg.v23.i25.4587 |
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author | Chen, Yu-Jung Chen, Kai-Wen Shih, Yu-Leung Su, Fang-Ying Lin, Yen-Po Meng, Fan-Chun Lin, Felicia Yu, Yun-Shun Han, Chih-Lu Wang, Chih-Hung Lin, Jia-Wei Hsieh, Tsai-Yuan Li, Yi-Hwei Lin, Gen-Min |
author_facet | Chen, Yu-Jung Chen, Kai-Wen Shih, Yu-Leung Su, Fang-Ying Lin, Yen-Po Meng, Fan-Chun Lin, Felicia Yu, Yun-Shun Han, Chih-Lu Wang, Chih-Hung Lin, Jia-Wei Hsieh, Tsai-Yuan Li, Yi-Hwei Lin, Gen-Min |
author_sort | Chen, Yu-Jung |
collection | PubMed |
description | AIM: To investigate the association of chronic hepatitis B and nonalcoholic steatohepatitis with physical fitness in a Taiwanese military male cohort. METHODS: We made a cross-sectional examination of this association using 3669 young adult military males according to cardiorespiratory fitness and hospitalization events recorded in the Taiwan Armed Forces study. Cases of chronic hepatitis B (n = 121) were defined by personal history and positive detection of hepatitis B surface antigen. Cases of nonalcoholic steatohepatitis (n = 129) were defined by alanine transaminase level > 60 U/L, liver ultrasound finding of steatosis, and absence of viral hepatitis A, B or C infection. All other study participants were defined as unaffected (n = 3419). Physical fitness was evaluated by performance in 3000-m run, 2-min sit-ups, and 2-min push-ups exercises, with all the procedures standardized by a computerized scoring system. Multiple linear regression analysis was used to determine the relationship. RESULTS: Chronic hepatitis B negatively correlated with 2-min push-up numbers (β = -2.49, P = 0.019) after adjusting for age, service specialty, body mass index, systolic and diastolic blood pressures, current cigarette smoking, alcohol intake status, serum hemoglobin, and average weekly exercise times. Nonalcoholic steatohepatitis was borderline positively correlated with 3000-m running time (β = 11.96, P = 0.084) and negatively correlated with 2-min sit-up numbers (β = -1.47, P = 0.040). CONCLUSION: Chronic hepatitis B viral infection and nonalcoholic steatohepatitis affects different physical performances in young adult military males, and future study should determine the underlying mechanism. |
format | Online Article Text |
id | pubmed-5504374 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-55043742017-07-24 Chronic hepatitis B, nonalcoholic steatohepatitis and physical fitness of military males: CHIEF study Chen, Yu-Jung Chen, Kai-Wen Shih, Yu-Leung Su, Fang-Ying Lin, Yen-Po Meng, Fan-Chun Lin, Felicia Yu, Yun-Shun Han, Chih-Lu Wang, Chih-Hung Lin, Jia-Wei Hsieh, Tsai-Yuan Li, Yi-Hwei Lin, Gen-Min World J Gastroenterol Retrospective Study AIM: To investigate the association of chronic hepatitis B and nonalcoholic steatohepatitis with physical fitness in a Taiwanese military male cohort. METHODS: We made a cross-sectional examination of this association using 3669 young adult military males according to cardiorespiratory fitness and hospitalization events recorded in the Taiwan Armed Forces study. Cases of chronic hepatitis B (n = 121) were defined by personal history and positive detection of hepatitis B surface antigen. Cases of nonalcoholic steatohepatitis (n = 129) were defined by alanine transaminase level > 60 U/L, liver ultrasound finding of steatosis, and absence of viral hepatitis A, B or C infection. All other study participants were defined as unaffected (n = 3419). Physical fitness was evaluated by performance in 3000-m run, 2-min sit-ups, and 2-min push-ups exercises, with all the procedures standardized by a computerized scoring system. Multiple linear regression analysis was used to determine the relationship. RESULTS: Chronic hepatitis B negatively correlated with 2-min push-up numbers (β = -2.49, P = 0.019) after adjusting for age, service specialty, body mass index, systolic and diastolic blood pressures, current cigarette smoking, alcohol intake status, serum hemoglobin, and average weekly exercise times. Nonalcoholic steatohepatitis was borderline positively correlated with 3000-m running time (β = 11.96, P = 0.084) and negatively correlated with 2-min sit-up numbers (β = -1.47, P = 0.040). CONCLUSION: Chronic hepatitis B viral infection and nonalcoholic steatohepatitis affects different physical performances in young adult military males, and future study should determine the underlying mechanism. Baishideng Publishing Group Inc 2017-07-07 2017-07-07 /pmc/articles/PMC5504374/ /pubmed/28740347 http://dx.doi.org/10.3748/wjg.v23.i25.4587 Text en ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. |
spellingShingle | Retrospective Study Chen, Yu-Jung Chen, Kai-Wen Shih, Yu-Leung Su, Fang-Ying Lin, Yen-Po Meng, Fan-Chun Lin, Felicia Yu, Yun-Shun Han, Chih-Lu Wang, Chih-Hung Lin, Jia-Wei Hsieh, Tsai-Yuan Li, Yi-Hwei Lin, Gen-Min Chronic hepatitis B, nonalcoholic steatohepatitis and physical fitness of military males: CHIEF study |
title | Chronic hepatitis B, nonalcoholic steatohepatitis and physical fitness of military males: CHIEF study |
title_full | Chronic hepatitis B, nonalcoholic steatohepatitis and physical fitness of military males: CHIEF study |
title_fullStr | Chronic hepatitis B, nonalcoholic steatohepatitis and physical fitness of military males: CHIEF study |
title_full_unstemmed | Chronic hepatitis B, nonalcoholic steatohepatitis and physical fitness of military males: CHIEF study |
title_short | Chronic hepatitis B, nonalcoholic steatohepatitis and physical fitness of military males: CHIEF study |
title_sort | chronic hepatitis b, nonalcoholic steatohepatitis and physical fitness of military males: chief study |
topic | Retrospective Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504374/ https://www.ncbi.nlm.nih.gov/pubmed/28740347 http://dx.doi.org/10.3748/wjg.v23.i25.4587 |
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