Psychological stress is related to a decrease of serum anti-müllerian hormone level in infertile women

BACKGROUND: Stress exposure has been proved to be linked to reproductive failure. The reproductive potential of women depends on the ovarian reserve. Anti-müllerian hormone (AMH) has been proved a reliable clinical marker of ovarian reserve. However, the correlation between psychological stress and...

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Detalles Bibliográficos
Autores principales: Dong, Yue-zhi, Zhou, Fei-jing, Sun, Ying-pu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504612/
https://www.ncbi.nlm.nih.gov/pubmed/28693593
http://dx.doi.org/10.1186/s12958-017-0271-4
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author Dong, Yue-zhi
Zhou, Fei-jing
Sun, Ying-pu
author_facet Dong, Yue-zhi
Zhou, Fei-jing
Sun, Ying-pu
author_sort Dong, Yue-zhi
collection PubMed
description BACKGROUND: Stress exposure has been proved to be linked to reproductive failure. The reproductive potential of women depends on the ovarian reserve. Anti-müllerian hormone (AMH) has been proved a reliable clinical marker of ovarian reserve. However, the correlation between psychological stress and AMH level is not clear. METHODS: A cross-sectional study including 576 women was conducted. AMH concentration was tested to reflect the ovarian reserve. Salivary alpha-amylase (SAA) level was measured to assess the stress of patients objectively. RESULTS: The SAA level was significantly, and negatively correlated with AMH levels in infertile women (r = −0.315, P = 0.000; adjusted for age, r = −0.336, P = 0.000). CONCLUSION: Higher psychological stress was related to a decreased AMH level in infertile women and psychological stress may affect ovarian reserve.
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spelling pubmed-55046122017-07-12 Psychological stress is related to a decrease of serum anti-müllerian hormone level in infertile women Dong, Yue-zhi Zhou, Fei-jing Sun, Ying-pu Reprod Biol Endocrinol Research BACKGROUND: Stress exposure has been proved to be linked to reproductive failure. The reproductive potential of women depends on the ovarian reserve. Anti-müllerian hormone (AMH) has been proved a reliable clinical marker of ovarian reserve. However, the correlation between psychological stress and AMH level is not clear. METHODS: A cross-sectional study including 576 women was conducted. AMH concentration was tested to reflect the ovarian reserve. Salivary alpha-amylase (SAA) level was measured to assess the stress of patients objectively. RESULTS: The SAA level was significantly, and negatively correlated with AMH levels in infertile women (r = −0.315, P = 0.000; adjusted for age, r = −0.336, P = 0.000). CONCLUSION: Higher psychological stress was related to a decreased AMH level in infertile women and psychological stress may affect ovarian reserve. BioMed Central 2017-07-11 /pmc/articles/PMC5504612/ /pubmed/28693593 http://dx.doi.org/10.1186/s12958-017-0271-4 Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Dong, Yue-zhi
Zhou, Fei-jing
Sun, Ying-pu
Psychological stress is related to a decrease of serum anti-müllerian hormone level in infertile women
title Psychological stress is related to a decrease of serum anti-müllerian hormone level in infertile women
title_full Psychological stress is related to a decrease of serum anti-müllerian hormone level in infertile women
title_fullStr Psychological stress is related to a decrease of serum anti-müllerian hormone level in infertile women
title_full_unstemmed Psychological stress is related to a decrease of serum anti-müllerian hormone level in infertile women
title_short Psychological stress is related to a decrease of serum anti-müllerian hormone level in infertile women
title_sort psychological stress is related to a decrease of serum anti-müllerian hormone level in infertile women
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504612/
https://www.ncbi.nlm.nih.gov/pubmed/28693593
http://dx.doi.org/10.1186/s12958-017-0271-4
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AT sunyingpu psychologicalstressisrelatedtoadecreaseofserumantimullerianhormonelevelininfertilewomen

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