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Overview of methodologies for T-cell receptor repertoire analysis

BACKGROUND: The T-cell receptor (TCR), located on the surface of T cells, is responsible for the recognition of the antigen-major histocompatibility complex, leading to the initiation of an inflammatory response. Analysing the TCR repertoire may help to gain a better understanding of the immune syst...

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Detalles Bibliográficos
Autores principales: Rosati, Elisa, Dowds, C Marie, Liaskou, Evaggelia, Henriksen, Eva Kristine Klemsdal, Karlsen, Tom H, Franke, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504616/
https://www.ncbi.nlm.nih.gov/pubmed/28693542
http://dx.doi.org/10.1186/s12896-017-0379-9