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PAT-H-MS coupled with laser microdissection to study histone post-translational modifications in selected cell populations from pathology samples
BACKGROUND: Aberrations in histone post-translational modifications (hPTMs) have been linked with various pathologies, including cancer, and could not only represent useful biomarkers but also suggest possible targetable epigenetic mechanisms. We have recently developed an approach, termed pathology...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504751/ https://www.ncbi.nlm.nih.gov/pubmed/28702092 http://dx.doi.org/10.1186/s13148-017-0369-8 |