Complete Genome Sequence and Comparative Genomics of a Streptococcus pyogenes emm3 Strain M3-b isolated from a Japanese Patient with Streptococcal Toxic Shock Syndrome

Epidemiologic typing of Streptococcus pyogenes (GAS) is frequently based on the genotype of the emm gene, which encodes M/Emm protein. In this study, the complete genome sequence of GAS emm3 strain M3-b, isolated from a patient with streptococcal toxic shock syndrome (STSS), was determined. This str...

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Autores principales: Ogura, Kohei, Watanabe, Shinya, Kirikae, Teruo, Miyoshi-Akiyama, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Short Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504827/
https://www.ncbi.nlm.nih.gov/pubmed/28698738
http://dx.doi.org/10.7150/jgen.20915
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author Ogura, Kohei
Watanabe, Shinya
Kirikae, Teruo
Miyoshi-Akiyama, Tohru
author_facet Ogura, Kohei
Watanabe, Shinya
Kirikae, Teruo
Miyoshi-Akiyama, Tohru
author_sort Ogura, Kohei
collection PubMed
description Epidemiologic typing of Streptococcus pyogenes (GAS) is frequently based on the genotype of the emm gene, which encodes M/Emm protein. In this study, the complete genome sequence of GAS emm3 strain M3-b, isolated from a patient with streptococcal toxic shock syndrome (STSS), was determined. This strain exhibited 99% identity with other complete genome sequences of emm3 strains MGAS315, SSI-1, and STAB902. The complete genomes of five additional strains isolated from Japanese patients with and without STSS were also sequences. Maximum-likelihood phylogenetic analysis showed that strains M3-b, M3-e, and SSI-1, all which were isolated from STSS patients, were relatively close.
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spelling pubmed-55048272017-07-11 Complete Genome Sequence and Comparative Genomics of a Streptococcus pyogenes emm3 Strain M3-b isolated from a Japanese Patient with Streptococcal Toxic Shock Syndrome Ogura, Kohei Watanabe, Shinya Kirikae, Teruo Miyoshi-Akiyama, Tohru J Genomics Short Research Paper Epidemiologic typing of Streptococcus pyogenes (GAS) is frequently based on the genotype of the emm gene, which encodes M/Emm protein. In this study, the complete genome sequence of GAS emm3 strain M3-b, isolated from a patient with streptococcal toxic shock syndrome (STSS), was determined. This strain exhibited 99% identity with other complete genome sequences of emm3 strains MGAS315, SSI-1, and STAB902. The complete genomes of five additional strains isolated from Japanese patients with and without STSS were also sequences. Maximum-likelihood phylogenetic analysis showed that strains M3-b, M3-e, and SSI-1, all which were isolated from STSS patients, were relatively close. Ivyspring International Publisher 2017-07-01 /pmc/articles/PMC5504827/ /pubmed/28698738 http://dx.doi.org/10.7150/jgen.20915 Text en © Ivyspring International Publisher This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Short Research Paper
Ogura, Kohei
Watanabe, Shinya
Kirikae, Teruo
Miyoshi-Akiyama, Tohru
Complete Genome Sequence and Comparative Genomics of a Streptococcus pyogenes emm3 Strain M3-b isolated from a Japanese Patient with Streptococcal Toxic Shock Syndrome
title Complete Genome Sequence and Comparative Genomics of a Streptococcus pyogenes emm3 Strain M3-b isolated from a Japanese Patient with Streptococcal Toxic Shock Syndrome
title_full Complete Genome Sequence and Comparative Genomics of a Streptococcus pyogenes emm3 Strain M3-b isolated from a Japanese Patient with Streptococcal Toxic Shock Syndrome
title_fullStr Complete Genome Sequence and Comparative Genomics of a Streptococcus pyogenes emm3 Strain M3-b isolated from a Japanese Patient with Streptococcal Toxic Shock Syndrome
title_full_unstemmed Complete Genome Sequence and Comparative Genomics of a Streptococcus pyogenes emm3 Strain M3-b isolated from a Japanese Patient with Streptococcal Toxic Shock Syndrome
title_short Complete Genome Sequence and Comparative Genomics of a Streptococcus pyogenes emm3 Strain M3-b isolated from a Japanese Patient with Streptococcal Toxic Shock Syndrome
title_sort complete genome sequence and comparative genomics of a streptococcus pyogenes emm3 strain m3-b isolated from a japanese patient with streptococcal toxic shock syndrome
topic Short Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504827/
https://www.ncbi.nlm.nih.gov/pubmed/28698738
http://dx.doi.org/10.7150/jgen.20915
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