The impact of spatial arrangements on epidemic disease dynamics and intervention strategies

The role of spatial arrangements on the spread and management strategies of a cholera epidemic is investigated. We consider the effect of human and pathogen movement on optimal vaccination strategies. A metapopulation model is used, incorporating a susceptible–infected–recovered system of differenti...

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Autores principales: Kelly, Michael R., Tien, Joseph H., Eisenberg, Marisa C., Lenhart, Suzanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504920/
https://www.ncbi.nlm.nih.gov/pubmed/26981710
http://dx.doi.org/10.1080/17513758.2016.1156172
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author Kelly, Michael R.
Tien, Joseph H.
Eisenberg, Marisa C.
Lenhart, Suzanne
author_facet Kelly, Michael R.
Tien, Joseph H.
Eisenberg, Marisa C.
Lenhart, Suzanne
author_sort Kelly, Michael R.
collection PubMed
description The role of spatial arrangements on the spread and management strategies of a cholera epidemic is investigated. We consider the effect of human and pathogen movement on optimal vaccination strategies. A metapopulation model is used, incorporating a susceptible–infected–recovered system of differential equations coupled with an equation modelling the concentration of Vibrio cholerae in an aquatic reservoir. The model compared spatial arrangements and varying scenarios to draw conclusions on how to effectively manage outbreaks. The work is motivated by the 2010 cholera outbreak in Haiti. Results give guidance for vaccination strategies in response to an outbreak.
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spelling pubmed-55049202017-07-11 The impact of spatial arrangements on epidemic disease dynamics and intervention strategies Kelly, Michael R. Tien, Joseph H. Eisenberg, Marisa C. Lenhart, Suzanne J Biol Dyn Article The role of spatial arrangements on the spread and management strategies of a cholera epidemic is investigated. We consider the effect of human and pathogen movement on optimal vaccination strategies. A metapopulation model is used, incorporating a susceptible–infected–recovered system of differential equations coupled with an equation modelling the concentration of Vibrio cholerae in an aquatic reservoir. The model compared spatial arrangements and varying scenarios to draw conclusions on how to effectively manage outbreaks. The work is motivated by the 2010 cholera outbreak in Haiti. Results give guidance for vaccination strategies in response to an outbreak. 2016 /pmc/articles/PMC5504920/ /pubmed/26981710 http://dx.doi.org/10.1080/17513758.2016.1156172 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Article
Kelly, Michael R.
Tien, Joseph H.
Eisenberg, Marisa C.
Lenhart, Suzanne
The impact of spatial arrangements on epidemic disease dynamics and intervention strategies
title The impact of spatial arrangements on epidemic disease dynamics and intervention strategies
title_full The impact of spatial arrangements on epidemic disease dynamics and intervention strategies
title_fullStr The impact of spatial arrangements on epidemic disease dynamics and intervention strategies
title_full_unstemmed The impact of spatial arrangements on epidemic disease dynamics and intervention strategies
title_short The impact of spatial arrangements on epidemic disease dynamics and intervention strategies
title_sort impact of spatial arrangements on epidemic disease dynamics and intervention strategies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504920/
https://www.ncbi.nlm.nih.gov/pubmed/26981710
http://dx.doi.org/10.1080/17513758.2016.1156172
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