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Clinical Characteristics and Risk Factors of Recurrent Mooren's Ulcer

PURPOSE: To investigate the clinical characteristics of Mooren's ulcer in East China and to identify the potential risk factors that affect the recurrence of Mooren's ulcer. METHODS: We reviewed the medical records of 95 patients (100 eyes) diagnosed with Mooren's ulcer from May 2005...

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Autores principales: Yang, Lixia, Xiao, Juan, Wang, Jiawei, Zhang, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504946/
https://www.ncbi.nlm.nih.gov/pubmed/28740737
http://dx.doi.org/10.1155/2017/8978527
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author Yang, Lixia
Xiao, Juan
Wang, Jiawei
Zhang, Han
author_facet Yang, Lixia
Xiao, Juan
Wang, Jiawei
Zhang, Han
author_sort Yang, Lixia
collection PubMed
description PURPOSE: To investigate the clinical characteristics of Mooren's ulcer in East China and to identify the potential risk factors that affect the recurrence of Mooren's ulcer. METHODS: We reviewed the medical records of 95 patients (100 eyes) diagnosed with Mooren's ulcer from May 2005 to December 2014. The patients were classified into recurrent and nonrecurrent groups and followed up for 18 months. The difference between two groups was estimated. The patients in the recurrent group were subdivided according to the history of corneal infection and corneal perforation, respectively. The recurrent time in the subgroups was analyzed. RESULTS: Patients in the recurrent group were more likely to have a history of corneal infection and corneal perforation than that in the nonrecurrent groups. In patients with recurrent Mooren's ulcer, the median time to first recurrence was 130 days in the infection group, 480 days in noninfection group, and 195 days in the perforation group versus 480 days in nonperforation group. CONCLUSION: Corneal infection and corneal perforation were associated with early recurrence of Mooren's ulcer. The tailored follow-up schedule should be used for patients with corneal infection and corneal perforation due to the high risk of recurrence.
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spelling pubmed-55049462017-07-24 Clinical Characteristics and Risk Factors of Recurrent Mooren's Ulcer Yang, Lixia Xiao, Juan Wang, Jiawei Zhang, Han J Ophthalmol Clinical Study PURPOSE: To investigate the clinical characteristics of Mooren's ulcer in East China and to identify the potential risk factors that affect the recurrence of Mooren's ulcer. METHODS: We reviewed the medical records of 95 patients (100 eyes) diagnosed with Mooren's ulcer from May 2005 to December 2014. The patients were classified into recurrent and nonrecurrent groups and followed up for 18 months. The difference between two groups was estimated. The patients in the recurrent group were subdivided according to the history of corneal infection and corneal perforation, respectively. The recurrent time in the subgroups was analyzed. RESULTS: Patients in the recurrent group were more likely to have a history of corneal infection and corneal perforation than that in the nonrecurrent groups. In patients with recurrent Mooren's ulcer, the median time to first recurrence was 130 days in the infection group, 480 days in noninfection group, and 195 days in the perforation group versus 480 days in nonperforation group. CONCLUSION: Corneal infection and corneal perforation were associated with early recurrence of Mooren's ulcer. The tailored follow-up schedule should be used for patients with corneal infection and corneal perforation due to the high risk of recurrence. Hindawi 2017 2017-06-27 /pmc/articles/PMC5504946/ /pubmed/28740737 http://dx.doi.org/10.1155/2017/8978527 Text en Copyright © 2017 Lixia Yang et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Yang, Lixia
Xiao, Juan
Wang, Jiawei
Zhang, Han
Clinical Characteristics and Risk Factors of Recurrent Mooren's Ulcer
title Clinical Characteristics and Risk Factors of Recurrent Mooren's Ulcer
title_full Clinical Characteristics and Risk Factors of Recurrent Mooren's Ulcer
title_fullStr Clinical Characteristics and Risk Factors of Recurrent Mooren's Ulcer
title_full_unstemmed Clinical Characteristics and Risk Factors of Recurrent Mooren's Ulcer
title_short Clinical Characteristics and Risk Factors of Recurrent Mooren's Ulcer
title_sort clinical characteristics and risk factors of recurrent mooren's ulcer
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504946/
https://www.ncbi.nlm.nih.gov/pubmed/28740737
http://dx.doi.org/10.1155/2017/8978527
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