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Low active loading of cargo into engineered extracellular vesicles results in inefficient miRNA mimic delivery
Extracellular vesicles (EVs) hold great potential as novel systems for nucleic acid delivery due to their natural composition. Our goal was to load EVs with microRNA that are synthesized by the cells that produce the EVs. HEK293T cells were engineered to produce EVs expressing a lysosomal associated...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505005/ https://www.ncbi.nlm.nih.gov/pubmed/28717424 http://dx.doi.org/10.1080/20013078.2017.1333882 |