YD277 Suppresses Triple-Negative Breast Cancer Partially Through Activating the Endoplasmic Reticulum Stress Pathway

Triple-negative breast cancer (TNBC) is an aggressive malignancy with poor clinical outcomes. YD277 is a novel small molecule derived from ML264, a KLF5 inhibitor that elicits cytotoxic effects in colon cancer cell lines. Our previous studies suggest that Krüpple-like factor 5 (KLF5) is a promising...

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Detalles Bibliográficos
Autores principales: Chen, Zekun, Wu, Qiuju, Ding, Ye, Zhou, Wenhui, Liu, Rong, Chen, Haiying, Zhou, Jia, Feng, Jing, Chen, Ceshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505065/
https://www.ncbi.nlm.nih.gov/pubmed/28740556
http://dx.doi.org/10.7150/thno.17555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505065/
https://www.ncbi.nlm.nih.gov/pubmed/28740556
http://dx.doi.org/10.7150/thno.17555

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