Therapeutic value of 3-D printing template-assisted (125)I-seed implantation in the treatment of malignant liver tumors

OBJECTIVE: To explore the therapeutic value of 3-D printing template-assisted (125)I-seed implantation in the treatment of malignant liver tumors. MATERIALS AND METHODS: Fifteen liver cancer patients with 47 total lesions were treated with 3-D printing template-assisted radioactive seed implantation...

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Detalles Bibliográficos
Autores principales: Han, Tao, Yang, Xiaodan, Xu, Ying, Zheng, Zhendong, Yan, Ying, Wang, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505618/
https://www.ncbi.nlm.nih.gov/pubmed/28740402
http://dx.doi.org/10.2147/OTT.S134290
Descripción
Sumario:OBJECTIVE: To explore the therapeutic value of 3-D printing template-assisted (125)I-seed implantation in the treatment of malignant liver tumors. MATERIALS AND METHODS: Fifteen liver cancer patients with 47 total lesions were treated with 3-D printing template-assisted radioactive seed implantation (group A), and 25 liver-tumor patients with 66 total lesions were treated with (125)I-seed implantation without a template auxiliary (group B). Operation time, in-hospital time, operation complications, dose distribution, and response rate (number) were compared between the two groups. RESULTS: Shorter operation times and better dose distribution were observed in group A than in group B, and the differences were statistically significant. The response rate after 2 months was 86.7% (13 of 15) in group A and 84% (21 of 25) in group B; differences between the two groups were not significant. CONCLUSION: Application of 3-D printing template-assisted radioactive seed implantation in the treatment of malignant liver tumors can help shorten operation time and optimize radiation-dose distribution, is worthy of further study, and has clinical significance.

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