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ADF/Cofilin Accelerates Actin Dynamics by Severing Filaments and Promoting Their Depolymerization at Both Ends
Actin-depolymerizing factor (ADF)/cofilins contribute to cytoskeletal dynamics by promoting rapid actin filament disassembly. In the classical view, ADF/cofilin sever filaments, and capping proteins block filament barbed ends whereas pointed ends depolymerize, at a rate that is still debated. Here,...
Autores principales: | Wioland, Hugo, Guichard, Berengere, Senju, Yosuke, Myram, Sarah, Lappalainen, Pekka, Jégou, Antoine, Romet-Lemonne, Guillaume |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505867/ https://www.ncbi.nlm.nih.gov/pubmed/28625781 http://dx.doi.org/10.1016/j.cub.2017.05.048 |
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