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Structures of RNA Polymerase Closed and Intermediate Complexes Reveal Mechanisms of DNA Opening and Transcription Initiation

Gene transcription is carried out by RNA polymerases (RNAPs). For transcription to occur, the closed promoter complex (RPc), where DNA is double stranded, must isomerize into an open promoter complex (RPo), where the DNA is melted out into a transcription bubble and the single-stranded template DNA...

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Detalles Bibliográficos
Autores principales:	Glyde, Robert, Ye, Fuzhou, Darbari, Vidya Chandran, Zhang, Nan, Buck, Martin, Zhang, Xiaodong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505868/ https://www.ncbi.nlm.nih.gov/pubmed/28579332 http://dx.doi.org/10.1016/j.molcel.2017.05.010

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