Pregnancy Is a Risk Factor for Secondary Focal Segmental Glomerulosclerosis in Women with a History of Very Low Birth Weight

Low birth weight (LBW) has been known to increase the susceptibility to renal injury in adulthood. A 26-year-old woman developed proteinuria in early pregnancy; she had been born with very LBW. The clinical course was progressive, and an emergency Caesarean section was performed at 36 weeks due to a...

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Detalles Bibliográficos
Autores principales: Tanaka, Mari, Iwanari, Sachio, Tsujimoto, Yasushi, Taniguchi, Keisuke, Hagihara, Koichiro, Fumihara, Daiki, Miki, Syo, Shimoda, Saeko, Ikeda, Masaki, Takeoka, Hiroya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505910/
https://www.ncbi.nlm.nih.gov/pubmed/28626180
http://dx.doi.org/10.2169/internalmedicine.56.8032
Descripción
Sumario:Low birth weight (LBW) has been known to increase the susceptibility to renal injury in adulthood. A 26-year-old woman developed proteinuria in early pregnancy; she had been born with very LBW. The clinical course was progressive, and an emergency Caesarean section was performed at 36 weeks due to acute kidney injury. A renal biopsy provided a diagnosis of post-adaptive focal segmental glomerulosclerosis. Increased demand for glomerular filtration during early pregnancy appeared to have initiated the renal injury. This report highlights the fact that pregnancy might be a risk factor for renal injury in women born with LBW.

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