Small Cell Lung Cancer in a 20-year-old Non-Smoking Man with Systemic Sclerosis

Small cell lung cancer (SCLC) is a neuroendocrine tumor, and the median age of onset is about 70 years old. A 20-year-old non-smoking man with known systemic sclerosis presented with discomfort in his left chest. Chest X-ray showed a mass shadow in the left upper zone. A transbronchial lung biopsy r...

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Autores principales: Saito, Go, Jinta, Torahiko, Nakaoka, Hiroshi, Kitamura, Atsushi, Yamaguchi, Kenichi, Nishimura, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505912/
https://www.ncbi.nlm.nih.gov/pubmed/28626182
http://dx.doi.org/10.2169/internalmedicine.56.7985
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author Saito, Go
Jinta, Torahiko
Nakaoka, Hiroshi
Kitamura, Atsushi
Yamaguchi, Kenichi
Nishimura, Naoki
author_facet Saito, Go
Jinta, Torahiko
Nakaoka, Hiroshi
Kitamura, Atsushi
Yamaguchi, Kenichi
Nishimura, Naoki
author_sort Saito, Go
collection PubMed
description Small cell lung cancer (SCLC) is a neuroendocrine tumor, and the median age of onset is about 70 years old. A 20-year-old non-smoking man with known systemic sclerosis presented with discomfort in his left chest. Chest X-ray showed a mass shadow in the left upper zone. A transbronchial lung biopsy revealed small cell carcinoma, and imaging studies reached the diagnosis of extensive disease small cell lung cancer. He had concurrent interstitial lung disease with a non-specific interstitial pneumonia pattern and anti-Scl-70 antibodies. He died eight months after the diagnosis during fifth-line chemotherapy. We herein report the youngest case to date of SCLC with systemic sclerosis.
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spelling pubmed-55059122017-07-14 Small Cell Lung Cancer in a 20-year-old Non-Smoking Man with Systemic Sclerosis Saito, Go Jinta, Torahiko Nakaoka, Hiroshi Kitamura, Atsushi Yamaguchi, Kenichi Nishimura, Naoki Intern Med Case Report Small cell lung cancer (SCLC) is a neuroendocrine tumor, and the median age of onset is about 70 years old. A 20-year-old non-smoking man with known systemic sclerosis presented with discomfort in his left chest. Chest X-ray showed a mass shadow in the left upper zone. A transbronchial lung biopsy revealed small cell carcinoma, and imaging studies reached the diagnosis of extensive disease small cell lung cancer. He had concurrent interstitial lung disease with a non-specific interstitial pneumonia pattern and anti-Scl-70 antibodies. He died eight months after the diagnosis during fifth-line chemotherapy. We herein report the youngest case to date of SCLC with systemic sclerosis. The Japanese Society of Internal Medicine 2017-06-15 /pmc/articles/PMC5505912/ /pubmed/28626182 http://dx.doi.org/10.2169/internalmedicine.56.7985 Text en Copyright © 2017 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Saito, Go
Jinta, Torahiko
Nakaoka, Hiroshi
Kitamura, Atsushi
Yamaguchi, Kenichi
Nishimura, Naoki
Small Cell Lung Cancer in a 20-year-old Non-Smoking Man with Systemic Sclerosis
title Small Cell Lung Cancer in a 20-year-old Non-Smoking Man with Systemic Sclerosis
title_full Small Cell Lung Cancer in a 20-year-old Non-Smoking Man with Systemic Sclerosis
title_fullStr Small Cell Lung Cancer in a 20-year-old Non-Smoking Man with Systemic Sclerosis
title_full_unstemmed Small Cell Lung Cancer in a 20-year-old Non-Smoking Man with Systemic Sclerosis
title_short Small Cell Lung Cancer in a 20-year-old Non-Smoking Man with Systemic Sclerosis
title_sort small cell lung cancer in a 20-year-old non-smoking man with systemic sclerosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5505912/
https://www.ncbi.nlm.nih.gov/pubmed/28626182
http://dx.doi.org/10.2169/internalmedicine.56.7985
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