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Molecular dynamics study on the mechanism of polynucleotide encapsulation by chitosan
The safe and effective delivery of therapeutic genes into target cell interiors is of great importance in gene therapy. Chitosan has been extensively studied as a gene delivery carrier due to its good biocompatibility and biodegradability. Understanding the atomic interaction mechanism between chito...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506017/ https://www.ncbi.nlm.nih.gov/pubmed/28698591 http://dx.doi.org/10.1038/s41598-017-05197-0 |