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Identification of differentially methylated BRCA1 and CRISP2 DNA regions as blood surrogate markers for cardiovascular disease

Genome-wide Illumina InfiniumMethylation 450 K DNA methylation analysis was performed on blood samples from clinical atherosclerosis patients (n = 8) and healthy donors (n = 8) in the LVAD study (NCT02174133, NCT01799005). Multiple differentially methylated regions (DMR) could be identified in ather...

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Detalles Bibliográficos
Autores principales: Istas, Geoffrey, Declerck, Ken, Pudenz, Maria, Szic, Katarzyna Szarc vel, Lendinez-Tortajada, Veronica, Leon-Latre, Montserrat, Heyninck, Karen, Haegeman, Guy, Casasnovas, Jose A., Tellez-Plaza, Maria, Gerhauser, Clarissa, Heiss, Christian, Rodriguez-Mateos, Ana, Berghe, Wim Vanden
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506022/
https://www.ncbi.nlm.nih.gov/pubmed/28698603
http://dx.doi.org/10.1038/s41598-017-03434-0

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