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Quality Measurement of Two-dimensional Shear Wave Speed Imaging for Breast Lesions: the Associated Factors and the Impact to Diagnostic Performance
This study aimed to identify the associated factors for quality measurement (QM) of shear wave speed (SWS) imaging and to validate the additional value of QM in the diagnosis of breast lesions. From September 2014 to February 2015, conventional ultrasound and SWS imaging were performed in 338 women...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506023/ https://www.ncbi.nlm.nih.gov/pubmed/28698632 http://dx.doi.org/10.1038/s41598-017-05281-5 |
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author | Li, Dan-Dan Xu, Hui-Xiong Liu, Bo-Ji Bo, Xiao-Wan Li, Xiao-Long Wu, Rong |
author_facet | Li, Dan-Dan Xu, Hui-Xiong Liu, Bo-Ji Bo, Xiao-Wan Li, Xiao-Long Wu, Rong |
author_sort | Li, Dan-Dan |
collection | PubMed |
description | This study aimed to identify the associated factors for quality measurement (QM) of shear wave speed (SWS) imaging and to validate the additional value of QM in the diagnosis of breast lesions. From September 2014 to February 2015, conventional ultrasound and SWS imaging were performed in 338 women with 361 breast lesions. Binary logistic regression was used to identify associated factors for QM. Sensitivity, specificity and the area under receiver operating characteristic (ROC) curve (AUC) among maximum SWS (SWS(max)), QM and SWS(max) plus QM (SWS(max)+QM) were compared to validate additional value of QM. Pathology confirmed 263 (72.9%) benign lesions and 98 (27.1%) malignancies. Maximum depth (Odds ratio [OR]: 1.398) and posterior features (OR: 1.206) were identified as independent associated factors for QM. Compared with SWS(max) and QM, the sensitivity of SWS(max)+QM increased from 67.3%, 64.3% to 83.7% whereas the specificity decreased from 90.5%, 72.6% to 65.4% (all P < 0.05). SWS(max) had the highest AUC in comparison with QM and SWS(max)+QM (0.849 vs. 0.685 vs. 0.745; P < 0.05). QM for breast lesions is associated with maximum depth and posterior features. Adding QM to SWS(max) is useful for breast cancer screening and SWS(max) alone is useful for breast cancer differentiation. |
format | Online Article Text |
id | pubmed-5506023 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-55060232017-07-13 Quality Measurement of Two-dimensional Shear Wave Speed Imaging for Breast Lesions: the Associated Factors and the Impact to Diagnostic Performance Li, Dan-Dan Xu, Hui-Xiong Liu, Bo-Ji Bo, Xiao-Wan Li, Xiao-Long Wu, Rong Sci Rep Article This study aimed to identify the associated factors for quality measurement (QM) of shear wave speed (SWS) imaging and to validate the additional value of QM in the diagnosis of breast lesions. From September 2014 to February 2015, conventional ultrasound and SWS imaging were performed in 338 women with 361 breast lesions. Binary logistic regression was used to identify associated factors for QM. Sensitivity, specificity and the area under receiver operating characteristic (ROC) curve (AUC) among maximum SWS (SWS(max)), QM and SWS(max) plus QM (SWS(max)+QM) were compared to validate additional value of QM. Pathology confirmed 263 (72.9%) benign lesions and 98 (27.1%) malignancies. Maximum depth (Odds ratio [OR]: 1.398) and posterior features (OR: 1.206) were identified as independent associated factors for QM. Compared with SWS(max) and QM, the sensitivity of SWS(max)+QM increased from 67.3%, 64.3% to 83.7% whereas the specificity decreased from 90.5%, 72.6% to 65.4% (all P < 0.05). SWS(max) had the highest AUC in comparison with QM and SWS(max)+QM (0.849 vs. 0.685 vs. 0.745; P < 0.05). QM for breast lesions is associated with maximum depth and posterior features. Adding QM to SWS(max) is useful for breast cancer screening and SWS(max) alone is useful for breast cancer differentiation. Nature Publishing Group UK 2017-07-11 /pmc/articles/PMC5506023/ /pubmed/28698632 http://dx.doi.org/10.1038/s41598-017-05281-5 Text en © The Author(s) 2017 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Li, Dan-Dan Xu, Hui-Xiong Liu, Bo-Ji Bo, Xiao-Wan Li, Xiao-Long Wu, Rong Quality Measurement of Two-dimensional Shear Wave Speed Imaging for Breast Lesions: the Associated Factors and the Impact to Diagnostic Performance |
title | Quality Measurement of Two-dimensional Shear Wave Speed Imaging for Breast Lesions: the Associated Factors and the Impact to Diagnostic Performance |
title_full | Quality Measurement of Two-dimensional Shear Wave Speed Imaging for Breast Lesions: the Associated Factors and the Impact to Diagnostic Performance |
title_fullStr | Quality Measurement of Two-dimensional Shear Wave Speed Imaging for Breast Lesions: the Associated Factors and the Impact to Diagnostic Performance |
title_full_unstemmed | Quality Measurement of Two-dimensional Shear Wave Speed Imaging for Breast Lesions: the Associated Factors and the Impact to Diagnostic Performance |
title_short | Quality Measurement of Two-dimensional Shear Wave Speed Imaging for Breast Lesions: the Associated Factors and the Impact to Diagnostic Performance |
title_sort | quality measurement of two-dimensional shear wave speed imaging for breast lesions: the associated factors and the impact to diagnostic performance |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506023/ https://www.ncbi.nlm.nih.gov/pubmed/28698632 http://dx.doi.org/10.1038/s41598-017-05281-5 |
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