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Injectable hybrid system for strontium local delivery promotes bone regeneration in a rat critical-sized defect model
Strontium (Sr) has been described as having beneficial influence in bone strength and architecture. However, negative systemic effects have been reported on oral administration of Sr ranelate, leading to strict restrictions in clinical application. We hypothesized that local delivery of Sr improves...
Autores principales: | Henriques Lourenço, Ana, Neves, Nuno, Ribeiro-Machado, Cláudia, Sousa, Susana R., Lamghari, Meriem, Barrias, Cristina C., Trigo Cabral, Abel, Barbosa, Mário A., Ribeiro, Cristina C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506032/ https://www.ncbi.nlm.nih.gov/pubmed/28698571 http://dx.doi.org/10.1038/s41598-017-04866-4 |
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