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Metabolic reprogramming is associated with flavopiridol resistance in prostate cancer DU145 cells

Flavopiridol (FP) is a pan-cyclin dependent kinase inhibitor, which shows strong efficacy in inducing cancer cell apoptosis. Although FP is potent against most cancer cells in vitro, unfortunately it proved less efficacious in clinical trials in various aggressive cancers. To date, the molecular mec...

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Detalles Bibliográficos
Autores principales:	Li, Xiaoran, Lu, Jie, Kan, Quancheng, Li, Xiaoli, Fan, Qiong, Li, Yaqing, Huang, Ruixia, Slipicevic, Ana, Dong, Hiep Phuc, Eide, Lars, Wang, Junbai, Zhang, Hongquan, Berge, Viktor, Goscinski, Mariusz Adam, Kvalheim, Gunnar, Nesland, Jahn M., Suo, Zhenhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506068/ https://www.ncbi.nlm.nih.gov/pubmed/28698547 http://dx.doi.org/10.1038/s41598-017-05086-6

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