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Extrinsic Protein Tyrosine Phosphatase Non-Receptor 22 Signals Contribute to CD8 T Cell Exhaustion and Promote Persistence of Chronic Lymphocytic Choriomeningitis Virus Infection

A genetic variant of the protein tyrosine phosphatase non-receptor 22 (PTPN22) is associated with a wide range of autoimmune diseases; however, the reasons behind its prevalence in the general population remain not completely understood. Recent evidence highlights an important role of autoimmune sus...

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Detalles Bibliográficos
Autores principales:	Jofra, Tatiana, Galvani, Giuseppe, Kuka, Mirela, Di Fonte, Roberta, Mfarrej, Bechara G., Iannacone, Matteo, Salek-Ardakani, Shahram, Battaglia, Manuela, Fousteri, Georgia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506075/ https://www.ncbi.nlm.nih.gov/pubmed/28747914 http://dx.doi.org/10.3389/fimmu.2017.00811

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