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Neodymium-140 DOTA-LM3: Evaluation of an In Vivo Generator for PET with a Non-Internalizing Vector

(140)Nd (t(1/2) = 3.4 days), owing to its short-lived positron emitting daughter (140)Pr (t(1/2) = 3.4 min), has promise as an in vivo generator for positron emission tomography (PET). However, the electron capture decay of (140)Nd is chemically disruptive to macrocycle-based radiolabeling, meaning...

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Detalles Bibliográficos
Autores principales: Severin, Gregory W., Kristensen, Lotte K., Nielsen, Carsten H., Fonslet, Jesper, Jensen, Andreas I., Frellsen, Anders F., Jensen, K. M., Elema, Dennis R., Maecke, Helmut, Kjær, Andreas, Johnston, Karl, Köster, Ulli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506079/
https://www.ncbi.nlm.nih.gov/pubmed/28748183
http://dx.doi.org/10.3389/fmed.2017.00098