Acquired Senescent T-Cell Phenotype Correlates with Clinical Severity in GATA Binding Protein 2-Deficient Patients

GATA binding protein 2 (GATA2) deficiency is a rare disorder of hematopoiesis, lymphatics, and immunity caused by spontaneous or autosomal dominant mutations in the GATA2 gene. Clinical manifestations range from neutropenia, lymphedema, deafness, to severe viral and mycobacterial infections, bone ma...

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Detalles Bibliográficos
Autores principales: Ruiz-García, Raquel, Rodríguez-Vigil, Carmen, Marco, Francisco Manuel, Gallego-Bustos, Fernando, Castro-Panete, María José, Diez-Alonso, Laura, Muñoz-Ruiz, Carlos, Ruiz-Contreras, Jesús, Paz-Artal, Estela, González-Granado, Luis Ignacio, Allende, Luis Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506090/
https://www.ncbi.nlm.nih.gov/pubmed/28747912
http://dx.doi.org/10.3389/fimmu.2017.00802

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