Interferon-Gamma DNA Methylation Is Affected by Mycophenolic Acid but Not by Tacrolimus after T-Cell Activation

Immunosuppressive drug therapy is required to treat patients with autoimmune disease and patients who have undergone organ transplantation. The main targets of the immunosuppressive drugs tacrolimus and mycophenolic acid (MPA; the active metabolite of mycophenolate mofetil) are T cells. It is curren...

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Detalles Bibliográficos
Autores principales: Peters, Fleur S., Peeters, Annemiek M. A., Hofland, Leo J., Betjes, Michiel G. H., Boer, Karin, Baan, Carla C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506181/
https://www.ncbi.nlm.nih.gov/pubmed/28747916
http://dx.doi.org/10.3389/fimmu.2017.00822

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