F1 Domain of the Leishmania (Leishmania) donovani Nucleoside Hydrolase Promotes a Th1 Response in Leishmania (Leishmania) infantum Cured Patients and in Asymptomatic Individuals Living in an Endemic Area of Leishmaniasis

The Leishmania (Leishmania) donovani nucleoside hydrolase NH36 is the main antigen of the Leishmune(®) vaccine and one of the promising candidates for vaccination against visceral leishmaniasis. The antigenicity of the N-terminal (F1), the central (F2), or the C-terminal recombinant domain (F3) of N...

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Detalles Bibliográficos
Autores principales: Carrillo, Eugenia, Fernandez, Laura, Ibarra-Meneses, Ana Victoria, Santos, Micheli L. B., Nico, Dirlei, de Luca, Paula M., Correa, Cristiane Bani, de Almeida, Roque Pacheco, Moreno, Javier, Palatnik-de-Sousa, Clarisa B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506215/
https://www.ncbi.nlm.nih.gov/pubmed/28747911
http://dx.doi.org/10.3389/fimmu.2017.00750

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