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Interpreting findings from Mendelian randomization using the MR-Egger method

Mendelian randomization-Egger (MR-Egger) is an analysis method for Mendelian randomization using summarized genetic data. MR-Egger consists of three parts: (1) a test for directional pleiotropy, (2) a test for a causal effect, and (3) an estimate of the causal effect. While conventional analysis met...

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Detalles Bibliográficos
Autores principales: Burgess, Stephen, Thompson, Simon G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506233/
https://www.ncbi.nlm.nih.gov/pubmed/28527048
http://dx.doi.org/10.1007/s10654-017-0255-x