Autophagy compensates impaired energy metabolism in CLPXP‐deficient Podospora anserina strains and extends healthspan

The degradation of nonfunctional mitochondrial proteins is of fundamental relevance for maintenance of cellular homeostasis. The heteromeric CLPXP protein complex in the mitochondrial matrix is part of this process. In the fungal aging model Podospora anserina, ablation of CLPXP leads to an increase...

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Detalles Bibliográficos
Autores principales: Knuppertz, Laura, Osiewacz, Heinz D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506401/
https://www.ncbi.nlm.nih.gov/pubmed/28449241
http://dx.doi.org/10.1111/acel.12600

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506401/
https://www.ncbi.nlm.nih.gov/pubmed/28449241
http://dx.doi.org/10.1111/acel.12600

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