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Autophagy compensates impaired energy metabolism in CLPXP‐deficient Podospora anserina strains and extends healthspan
The degradation of nonfunctional mitochondrial proteins is of fundamental relevance for maintenance of cellular homeostasis. The heteromeric CLPXP protein complex in the mitochondrial matrix is part of this process. In the fungal aging model Podospora anserina, ablation of CLPXP leads to an increase...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5506401/ https://www.ncbi.nlm.nih.gov/pubmed/28449241 http://dx.doi.org/10.1111/acel.12600 |